Physician-Led Medical Spa in San Francisco
Medical Spa & Regenerative Wellness in San Francisco
Look younger. Feel stronger. Live longer.
Premier Wellness & Aesthetics is a physician-led medical spa in San Francisco, CA, where Dr. Harlan South, MD helps patients explore stem cell-focused regenerative wellness, hormone optimization, TRT/HRT, longevity programs, and aesthetic care through medically guided treatment planning.
Visit Our Medical Spa in San Francisco
Premier Wellness & Aesthetics Center · 490 Post St Ste 913, San Francisco, CA 94102
Personalized care designed around you
'%20fill='var(--21h8s6,%20rgb(0,%200,%200))'%20height='15px'%20id='y5z2UX80g'%20transform='translate(6%204.5)'%20width='12px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%209%200'%20fill='transparent'%20height='1px'%20id='xY0DzChgA'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(9%204.5)'%20width='9px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%200%202.578%20C%200%205.135%201.444%207.472%203.731%208.616%20L%208.269%2010.884%20C%2010.556%2012.028%2012%2014.365%2012%2016.922%20L%2012%2019.5'%20fill='transparent'%20height='19.5px'%20id='n6KihNTLG'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(6%202.25)'%20width='12px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%209%200'%20fill='transparent'%20height='1px'%20id='Z_jGoJdeW'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(6%2019.5)'%20width='9px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%207.334%200'%20fill='transparent'%20height='1px'%20id='SA8mAICXD'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(10.115%207.5)'%20width='7.334062500000002px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%207.334%200'%20fill='transparent'%20height='1px'%20id='nrbPpcDqm'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(6.551%2016.5)'%20width='7.334062500000002px'%3e%3c/path%3e%3cpath%20d='M%202.754%200%20C%201.023%201.272%200%203.292%200%205.44%20L%200%208.018'%20fill='transparent'%20height='8.018437500000005px'%20id='We6P8VjnX'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(6%2013.732)'%20width='2.754374999999996px'%3e%3c/path%3e%3cpath%20d='M%202.754%200%20L%202.754%202.578%20C%202.753%204.726%201.731%206.744%200%208.016'%20fill='transparent'%20height='8.015625px'%20id='sdR9Dt3W6'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(15.246%202.25)'%20width='2.7543750000000102px'%3e%3c/path%3e%3c/svg%3e){kind=small}
Personalized Evaluation
A medically guided consultation to discuss your goals, health history, symptoms, and relevant testing.
'%20fill='var(--21h8s6,%20rgb(0,%200,%200))'%20height='17.25px'%20id='cfOffjztF'%20transform='translate(4.5%203.75)'%20width='15px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%206%200'%20fill='transparent'%20height='1px'%20id='CK4Hjr5qd'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(9%2014.25)'%20width='6px'%3e%3c/path%3e%3cpath%20d='M%200%200%20L%206%200'%20fill='transparent'%20height='1px'%20id='PkHqDMqYh'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(9%2011.25)'%20width='6px'%3e%3c/path%3e%3cpath%20d='M%2010.5%200%20L%2014.25%200%20C%2014.664%200%2015%200.336%2015%200.75%20L%2015%2016.5%20C%2015%2016.914%2014.664%2017.25%2014.25%2017.25%20L%200.75%2017.25%20C%200.336%2017.25%200%2016.914%200%2016.5%20L%200%200.75%20C%200%200.336%200.336%200%200.75%200%20L%204.5%200'%20fill='transparent'%20height='17.25px'%20id='NCgd433kM'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(4.5%203.75)'%20width='15px'%3e%3c/path%3e%3cpath%20d='M%200%204.5%20L%200%203.75%20C%200%201.679%201.679%200%203.75%200%20C%205.821%200%207.5%201.679%207.5%203.75%20L%207.5%204.5%20Z'%20fill='transparent'%20height='4.5px'%20id='LnZBLQhtE'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(8.25%202.25)'%20width='7.5px'%3e%3c/path%3e%3c/svg%3e){kind=small}
Tailored Plan
Personalized treatment planning based on candidacy, clinical judgment, and the options discussed with you.
'%20fill='var(--21h8s6,%20rgb(0,%200,%200))'%20height='15.75px'%20id='g9binZL5z'%20transform='translate(5.25%203.75)'%20width='13.5px'%3e%3c/path%3e%3cpath%20d='M%200%208.25%20L%203%208.25%20L%206.75%200%20L%2012.75%2015.75%20L%2016.5%208.25%20L%2019.5%208.25'%20fill='transparent'%20height='15.75px'%20id='D2U_u1mAL'%20stroke-dasharray=''%20stroke-linecap='round'%20stroke-linejoin='round'%20stroke-width='var(--pgex8v,%201.5)'%20stroke='var(--21h8s6,%20rgb(0,%200,%200))'%20transform='translate(2.25%203.75)'%20width='19.5px'%3e%3c/path%3e%3c/svg%3e){kind=small}
Ongoing Follow-Up
Monitoring and follow-up designed to help the care plan evolve with your needs over time.
Medical Spa in San Francisco
Medical Spa Services in San Francisco
At Premier Wellness & Aesthetics, patients can explore physician-led aesthetic care, regenerative wellness, hormone optimization, and skin-focused treatment planning in San Francisco, CA. The homepage highlights the main ways our medical spa supports facial aesthetics, whole-body wellness, and clinical skin care.
BOTOX treatments
Botox in San Francisco →Dysport treatment
Injectables →EmSculpt treatments
Body Contouring →Lip fillers
Injectables & Fillers →PRP facial
Skin Rejuvenation →Xeomin
Injectables →Daxxify
Injectables →
Health Spa
Compare the broader hormone-therapy pathway with focused TRT and HRT consultations, and review consultation-based regenerative wellness and proactive longevity planning without one-size-fits-all promises.
Skin Care Clinic
Begin with a skin-focused assessment and discuss responsible rejuvenation or aesthetic options with the physician-led team.
Popular services in San Francisco
Hormone Therapy is the broader physician-led evaluation and planning path for patients exploring hormone balance. TRT refers to testosterone replacement therapy consultations for eligible patients, and HRT is a broader hormone replacement therapy planning path. Candidacy for each is determined during consultation with Dr. Harlan South, MD.
Physician-Led Care
Physician-Led Care With Dr. Harlan South, MD
At Premier Wellness & Aesthetics Center, care is medically guided by Dr. Harlan South, MD. Patients meet with a physician-led team to discuss aesthetic goals, hormone optimization, regenerative wellness options, and longevity-focused treatment planning in a responsible clinical setting.
Independent education & local access
Trusted Resources for Informed Conversations
These independent resources can help patients prepare questions about regenerative wellness, hormones, healthy aging, and visiting our downtown San Francisco office. They do not describe Premier treatment outcomes or replace individualized medical advice.
FDA regenerative medicine consumer information
Review how the FDA regulates regenerative medicine products and the questions patients should ask before considering care.
Visit official source →Endocrine Society testosterone information
Read independent patient education about evaluation, repeat testing, treatment considerations, and follow-up for low testosterone.
Visit official source →National Institute on Aging healthy-aging guidance
Explore research-informed information about lifestyle, preventive care, and maintaining health and function over time.
Visit official source →SFMTA Union Square transit and parking information
Plan a downtown visit using official San Francisco transit routes and nearby public parking information.
Visit official source →Our Services
Explore Our Services
Explore medically guided wellness and aesthetic services. Recommendations, candidacy, and expected outcomes vary by patient and are discussed during consultation.
Wellness Medicine
Personalized, medically guided programs for discussing hormone health, regenerative wellness, energy concerns, and longevity goals.
Aesthetics Medicine
Tailored treatments that rejuvenate skin, refine appearance, and restore confidence using advanced, results-driven aesthetic therapies.
Membership Plans
Experience personalized care with exclusive benefits
Core Hormone
Designed for medically guided hormone evaluation, personalized planning, monitoring, and follow-up.
Join Now
Flexible membership billed annually.
Includes:
- Comprehensive hormone lab panel
- Thyroid and adrenal function testing
- Personalized treatment plan with bioidentical therapy
- 1:1 physician-led results review
- Ongoing access to clinical support
- Quarterly progress evaluations
Longevity
Focused on optimizing healthspan and enhancing energy, cognition, and performance.
Join Now
Flexible membership billed annually.
Includes:
- Advanced biomarker and genetic testing
- Cardiovascular and metabolic health screening
- Peptide and supplement protocols
- Cognitive performance tracking
- Bi-annual provider consultations
- Quarterly progress evaluations
Gut Health
Designed to support digestive wellness through individualized testing, nutrition planning, and follow-up.
Join Now
Flexible membership billed annually.
Includes:
- Comprehensive stool and microbiome analysis
- Food sensitivity & inflammation testing
- Custom probiotic and nutrition plan
- Physician-led results interpretation
- Lifestyle and supplement guidance
- Continuous care and re-testing as needed
The Blog
Read More PostsThe Wellness Journal
Explore insights, science, and stories to help you feel and look your best from longevity to aesthetics.
Experience modern wellness in a serene, patient-focused space designed for comfort.
See Inside Premier WellnessMedical Spa in San Francisco, CA
Premier Wellness & Aesthetics Center
490 Post St Ste 913
San Francisco, CA 94102
Premier Wellness & Aesthetics Center offers physician-led regenerative wellness, hormone optimization, longevity, and aesthetic care with Dr. Harlan South, MD.
Start your journey to longevity and confidence
Experience personalized medicine that helps you feel stronger, age gracefully, and live with renewed energy and purpose.